Total Game Control -gives you exactly that... the ultimate control over your games.
It works by mapping keyboard, mouse, and other events of
your choosing to the controls on your game pad or joystick. You set
up the controls the way you want. Tie complex moves to a single
button, or map them to any combination of controls.

It even works with console game pads such as Sony Playstation, PS2,
Gamecube, XBox, etc. when connected through a PC adapter.

"Works great with my NYKO Air Flo PC USB GamePad that came with no
software support"